Image for Alizarin
Alizarin

Synonyms/Common Names/Related Substances:

  • Alizari (Arabic), alizarin fluorine blue, alizarin red, alizarin red S (ARS), alizarin S, alizarin sulfonic acid, alizarin yellow GG, alizarine, anthraquine, ARS, dyer's madder, faberrote, garance, Krapp, lake, madder, madder plant, robbia, rubia, Rubia tintorum, Rubia tinctorum L., Rubia tinctorum radix.

Clinical Bottom Line/Effectiveness

Brief Background:

  • Alizarin is a histochemical stain that highlights calcium. It is used by dermatopathologists to detect dermal calcium in disorders such as pseudoxanthoma elasticum and calcinosis cutis (1).
  • Originally alizarin vegetable dye was prepared from the madder plant Rubia tinctorum, but now a synthetic preparation is used which is chemically identical.
  • There are no well-established therapeutic uses of alizarin other than as a bone-marker or staining agent. However, one study investigated alizarin in the treatment of viral infections (2).
  • Precautions should be taken while handling this dye due to the unavailability of sufficient safety data (3).

Dosing/Toxicology

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Precautions/Contraindications

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Interactions

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

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Mechanism of Action

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History

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Evidence Table

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Evidence Discussion

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Products Studied

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Author Information

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References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.